MOLECULAR MECHANISM OF PAIN

Working with Dr. Theodore Price at UT Dallas and Dr. Angelo Lepore at TJU, we are examining novel mechanisms that regulate neuropathic pain and pain plasticity. 

​Our work focuses on a new type of extracellular interaction mediated by phosphorylation of EphB2 that is necessary and sufficient for the direct interaction between the NMDA-type glutamate receptor and the receptor tyrosine kinase EphB2. 

​Our current work builds on studies published in 2017 (Hanamura at el., PlosBiology 2017).

 

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