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Research Associate

 

We are currently looking for a talented and enthusiastic research associate!!

 

Dr. Dalva’s laboratory studies the mechanisms of synapse development and function in the brain and spinal cord. The structure of the nervous system varies tremendously across phylogeny; organisms such as the C. elegans function with a few hundred neurons, whereas humans have tens of billions. Yet communication in all neural circuits is controlled by a remarkably similar, highly specialized site of cell-cell contact known as a synapse. The long-range goal of my research is to discover how synapses are formed and lost, and what impact normal morphology and numbers of synapses have on brain function. Currently, my laboratory has a strong interest and background in super-resolution imaging and technology development. We have been using Stimulated Emission Depletion (STED) to examine the nanoscale organization of the synapse. We have also developed a number of genetically encoded reporters that enable visualization of tyrosine kinase activity in living cells. Determining how synapses develop and mature will provide insights toward the understanding of neuronal networks and brain function.

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Research Associate

 

We are currently looking for a talented and enthusiastic postdoctoral fellow or fellows.

 

Dr. Dalva’s laboratory studies the mechanisms of synapse development and function in the brain and spinal cord. The structure of the nervous system varies tremendously across phylogeny; organisms such as the C. elegans function with a few hundred neurons, whereas humans have tens of billions. Yet communication in all neural circuits is controlled by a remarkably similar, highly specialized site of cell-cell contact known as a synapse. The long-range goal of my research is to discover how synapses are formed and lost, and what impact normal morphology and numbers of synapses have on brain function. Currently, my laboratory has a strong interest and background in super-resolution imaging and technology development. We have been using Stimulated Emission Depletion (STED) to examine the nanoscale organization of the synapse. We have also developed a number of genetically encoded reporters that enable visualization of tyrosine kinase activity in living cells. Determining how synapses develop and mature will provide insights toward the understanding of neuronal networks and brain function.

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